Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(4-(4-[2-ethyl-phenylamino)-methylene]-3-methyl-5-oxo-4,5-dihydro-pyrazol-1-yl)-benzoic acid | 0.00001 mM, 50% inhibition | Canis lupus familiaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanosine 3',5'-cyclic phosphate + H2O | Canis lupus familiaris | - |
guanosine 5'-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | whole myocardium from failing hearts have 50% lower PDE5A expression and 30% less total and EMD82639-inhibitable cGMP-PDE activity | Canis lupus familiaris | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanosine 3',5'-cyclic phosphate + H2O | - |
Canis lupus familiaris | guanosine 5'-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDE5A | - |
Canis lupus familiaris |
phosphodiesterase 5 (cGMP-specific) | - |
Canis lupus familiaris |