Literature summary for 3.1.4.3 extracted from

Labriola, J.M.; daCosta, C.J.; Wang, S.; Figeys, D.; Smith, J.C.; Sturgeon, R.M.; Baenziger, J.E.
Phospholipase C activity affinity purifies with the Torpedo nicotinic acetylcholine receptor (2010), J. Biol. Chem., 285, 10337-10343.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no inhibition by N-ethylmaleimide	Tetronarce californica
Sodium vanadate	a lipid phosphate phosphohydrolase inhibitor	Tetronarce californica

Organism

Organism	UniProt	Comment	Textmining
Tetronarce californica	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphatidic acid + H2O	specific for	Tetronarce californica	1,2-diacyl-sn-glycerol + phosphate	-	?

General Information

General Information	Comment	Organism
physiological function	a phospholipase C activity, which appears to be specific for phosphatidic acid, is associated with the nicotinic acetylcholine receptor. The acetylcholine receptor may directly or indirectly influence lipid metabolism in a manner that enhances its own function	Tetronarce californica

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Release 2023.1 (January 2023)