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Literature summary for 3.1.4.17 extracted from
- Cyclic nucleotide phosphodiesterases (PDE) and peptide motifs (2010), Curr. Pharm. Des., 16, 1114-1125.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| sildenafil | viagra, potent selective PDE5 inhibitor | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nucleoside 3',5'-cyclic phosphate + H2O | Homo sapiens | - |
nucleoside 5'-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nucleoside 3',5'-cyclic phosphate + H2O | - |
Homo sapiens | nucleoside 5'-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cyclic nucleotide phosphodiesterase | - |
Homo sapiens |
| PDE3 | - |
Homo sapiens |
| PDE4 | - |
Homo sapiens |
| PDE5 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Calmodulin | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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