Application | Comment | Organism |
---|---|---|
medicine | PDE11 inhibition has impacts on sperm quality. Reasonable caution is indicated for patients taking the prescribed dosages of tadalafil, a PDE5 inhibitor which could crossreact with human PDE11A splicing variants | Homo sapiens |
medicine | PDE11 inhibition has impacts on sperm quality. Reasonable caution should by suggested in patients taking the prescribed dosages of tadalafil, a PDE5 inhibitor which could crossreact with human PDE11A splicing variants | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tadalafil | PDE11 inhibition has impacts on sperm quality. Reasonable caution should by suggested in patients taking the prescribed dosages of tadalafil, a PDE5 inhibitor which could crossreact with human PDE11A splicing variants | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | PDE11A2 | Homo sapiens | - |
lung | PDE11A2 | Homo sapiens | - |
prostate gland | PDE11A2 | Homo sapiens | - |
prostate gland | PDE11A4 | Homo sapiens | - |
skeletal muscle | PDE11A1 is predominantly present in | Homo sapiens | - |
skeletal muscle | PDE11A2 | Homo sapiens | - |
spleen | PDE11A2 | Homo sapiens | - |
testis | PDE11A2 | Homo sapiens | - |
testis | PDE11A3 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
PDE11A1 | - |
Homo sapiens |
PDE11A2 | - |
Homo sapiens |
PDE11A3 | - |
Homo sapiens |
PDE11A4 | - |
Homo sapiens |
phosphodiesterase 11 | - |
Homo sapiens |