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Literature summary for 3.1.4.17 extracted from

  • Pomara, G.; Morelli, G.
    Inhibition of phosphodiesterase 11 (PDE11) impact on sperm quality (2005), Int. J. Impot. Res., 17, 385-386.
    View publication on PubMed

Application

Application Comment Organism
medicine PDE11 inhibition has impacts on sperm quality. Reasonable caution is indicated for patients taking the prescribed dosages of tadalafil, a PDE5 inhibitor which could crossreact with human PDE11A splicing variants Homo sapiens
medicine PDE11 inhibition has impacts on sperm quality. Reasonable caution should by suggested in patients taking the prescribed dosages of tadalafil, a PDE5 inhibitor which could crossreact with human PDE11A splicing variants Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
tadalafil PDE11 inhibition has impacts on sperm quality. Reasonable caution should by suggested in patients taking the prescribed dosages of tadalafil, a PDE5 inhibitor which could crossreact with human PDE11A splicing variants Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain PDE11A2 Homo sapiens
-
lung PDE11A2 Homo sapiens
-
prostate gland PDE11A2 Homo sapiens
-
prostate gland PDE11A4 Homo sapiens
-
skeletal muscle PDE11A1 is predominantly present in Homo sapiens
-
skeletal muscle PDE11A2 Homo sapiens
-
spleen PDE11A2 Homo sapiens
-
testis PDE11A2 Homo sapiens
-
testis PDE11A3 Homo sapiens
-

Synonyms

Synonyms Comment Organism
PDE11A1
-
Homo sapiens
PDE11A2
-
Homo sapiens
PDE11A3
-
Homo sapiens
PDE11A4
-
Homo sapiens
phosphodiesterase 11
-
Homo sapiens