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Literature summary for 3.1.4.12 extracted from

  • Lansmann, S.; Ferlinz, K.; Hurwitz, R.; Bartelsen, O.; Glombitza, G.; Sandhoff, K.
    Purification of acid sphingomyelinase from human placenta: Characterization and N-terminal sequence (1996), FEBS Lett., 399, 227-231.
    View publication on PubMed
Search for more literature for 3.1.4.12

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.025
-
 sphingomyelin
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
 x * 75000 with SDS-PAGE and western blotting analysis, x * 60000 than deglycosylated Homo sapiens
75000
-
 x * 75000 with SDS-PAGE and western blotting analysis, x * 60000 than deglycosylated Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
110000fold Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 different assay conditions, substrates etc. Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sphingomyelin + H2O
-
 Homo sapiens N-acylsphingosine + choline phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 75000 with SDS-PAGE and western blotting analysis, x * 60000 than deglycosylated Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.6 4.7
-
 Homo sapiens