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BRENDA support

Literature summary for 3.1.4.11 extracted from

  • He, H.; Genovese, K.J.; Nisbet, D.J.; Kogut, M.H.
    Involvement of phosphatidylinositol-phospholipase C in immune response to Salmonella lipopolysacharide in chicken macrophage cells (HD11) (2006), Int. Immunopharmacol., 6, 1780-1787.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(1 -[6-[[17-beta-3-methoxyestra-1,3,5(10)-trien-17-yl]amino] hexyl]-1H-pyrrole-2,5-dione)
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Gallus gallus
edelfosin
-
Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Gallus gallus phosphatidylinositol-phospholipase C plays a critical role, most likely through activation of protein kinase C pathway, in TLR4 mediated immune responses of avian macrophage cells to lipopolysaccharides ?
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?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HD-11 cell macrophage cell line Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information phosphatidylinositol-phospholipase C plays a critical role, most likely through activation of protein kinase C pathway, in TLR4 mediated immune responses of avian macrophage cells to lipopolysaccharides Gallus gallus ?
-
?

Synonyms

Synonyms Comment Organism
PI-PLC
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Gallus gallus