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Literature summary for 3.1.4.11 extracted from

  • Yoon, H.J.; Park, S.W.; Lee, H.B.; Im, S.Y.; Hooper, N.M.; Park, H.S.
    Release of renal dipeptidase from glycosylphosphatidylinositol anchor by insulin-triggered phospholipase C/intracellular Ca2+ (2007), Arch. Pharm. Res., 30, 608-615.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Insulin in part, may activate GPI-PLC, via phosphatidylinositol-specific phospholipase C/intracellular Ca2+, which may consequently stimulate the release of GPI-renal dipeptidase Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
additional information D609 has no effect Sus scrofa
U73122 effectively blocks the effect of insulin on the release of GPI-renal dipeptidase Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Sus scrofa
-
proximal tubule
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GPI-renal dipeptidase
-
Sus scrofa ?
-
?

Synonyms

Synonyms Comment Organism
GPI-PLC
-
Sus scrofa
GPI-specific phospholipase C
-
Sus scrofa