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Literature summary for 3.1.4.11 extracted from

  • Crljen, V.; Visnjic, D.; Banfic, H.
    Presence of different phospholipase C isoforms in the nucleus and their activation during compensatory liver growth (2004), FEBS Lett., 571, 35-42.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
chromatin PLC-delta1 Rattus norvegicus 785
-
nucleus an early increase in PLC-beta1b activity (6 h after partial hepatectomy) in nuclear matrix is associated with serine phosphorylation of the enzyme, the later increase (20 h after partial hepatectomy) paralleles the increase in the amount of protein Rattus norvegicus 5634
-
nucleus nuclear matrix, PLC-gamma1 Rattus norvegicus 5634
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein an early increase in PLC-beta1b activity (6 h after partial hepatectomy) in nuclear matrix is associated with serine phosphorylation of the enzyme Rattus norvegicus
phosphoprotein the increase in the PLC-gamma1 activity measured at 6 h and 20 h after partial hepatectomy is associated with tyrosine phosphorylation of the enzyme Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver an early increase in PLC-beta1b activity (6 h after partial hepatectomy) in nuclear matrix is associated with serine phosphorylation of the enzyme, the later increase (20 h after partial hepatectomy) paralleles the increase in the amount of protein Rattus norvegicus
-
liver the activity of PLC-delta1 and the amount of protein found in chromatin is increased only at 20 h after partial hepatectomy Rattus norvegicus
-
liver the increase in the PLC-gamma1 activity measured at 6 h and 20 h after partial hepatectomy is associated with tyrosine phosphorylation of the enzyme Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O PLC beta1b Rattus norvegicus 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O PLC-delta1 Rattus norvegicus 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O PLC-gamma1 Rattus norvegicus 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
?

Synonyms

Synonyms Comment Organism
PLC beta1b
-
Rattus norvegicus
PLC-delta1
-
Rattus norvegicus
PLC-gamma1
-
Rattus norvegicus