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Literature summary for 3.1.4.11 extracted from

  • Hirasawa, K.; Irvine, R.F.; Dawson, R.M.C.
    Heterogeneity of the calcium-dependent phosphatidylinositol phosphodiesterase in rat brain (1982), Biochem. J., 205, 437-442.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.11

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylinositol + H2O
-
 Rattus norvegicus 1D-myo-inositol 1-phosphate + diacylglycerol in vitro also 1D-myo-inositol 1,2-cyclic phosphate formed ?

Synonyms

Synonyms Comment Organism
phosphatidylinositol phosphodiesterase phospholipase C-type Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
 assay at Rattus norvegicus
5.6
-
 when (NH4)2SO4 fractionation (30-50%) of the brain supernatant is carried out, the phosphodiesterase preparation obtained shows an optimum at pH 5.6 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
5 8.5
-
 Rattus norvegicus

pI Value

Organism Comment pI Value Maximum pI Value
Rattus norvegicus 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 4.2 3.8
Rattus norvegicus 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 4.8 4.4
Rattus norvegicus when assayed at pH 7.0 and pH 8.0, 1 mM Ca2+
-
 4.6
Rattus norvegicus 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5
-
 5.86
Rattus norvegicus 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 7.4 7.2