Inhibitors | Comment | Organism | Structure |
---|---|---|---|
neomycin | - |
Homo sapiens | |
neomycin | - |
Oryctolagus cuniculus | |
neomycin | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Homo sapiens | |
Ca2+ | activates | Rattus norvegicus | |
Ca2+ | activates | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Rattus norvegicus | - |
erythrocyte | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidylinositol 4,5-bisphosphate + H2O | enzyme attacks phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-phosphate with equal facility | Homo sapiens | D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? | |
phosphatidylinositol 4,5-bisphosphate + H2O | enzyme attacks phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-phosphate with equal facility | Rattus norvegicus | D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? | |
phosphatidylinositol 4,5-bisphosphate + H2O | enzyme attacks phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-phosphate with equal facility | Oryctolagus cuniculus | D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? | |
phosphatidylinositol 4-phosphate | enzyme attacks phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-phosphate with equal facility | Homo sapiens | ? | - |
? | |
phosphatidylinositol 4-phosphate | enzyme attacks phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-phosphate with equal facility | Rattus norvegicus | ? | - |
? | |
phosphatidylinositol 4-phosphate | enzyme attacks phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-phosphate with equal facility | Oryctolagus cuniculus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | - |
hydrolysis of phosphatidylinositol 4,5-diphosphate | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.7 | 8 | pH 5.7: about 70% of maximal activity, pH 8.0: about 50% of maximal activity | Homo sapiens |