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Literature summary for 3.1.4.1 extracted from
- Characterization of renal ecto-phosphodiesterase (2007), J. Pharmacol. Exp. Ther., 321, 810-815.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dipyramidole | 0.1 mM, inhibition, no inhibition at 0.003 mM | Rattus norvegicus |  |
| additional information | not inhibitory to renal ecto-phosphodiesterase: 8-methoxymethyl-3-isobutyl-1-methylxanthine, erythro-9-(2-hydroxy-3-nonyl)adenine, milrinone, cGMP, 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one, zaprinast, 5-nitro-2,N,N-trimethylbenzenesulfonamide | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | ecto-phosphodiesterase activity is not mediated by isoform PDE1, PDE2, PDE3, PDE4, PDE5, PDE6, PDE7, PDE9, PDE10,or PDE11 activity | Rattus norvegicus | - |
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