Any feedback?
Literature summary for 3.1.4.1 extracted from
- Tissue and intracellular distribution of two phophodiesterases (1961), J. Biol. Chem., 236, 3028-3030.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Homo sapiens |  |
| EDTA | - |
Rattus norvegicus | |
| EDTA | - |
Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Sus scrofa | 5764 | - |
| microsome | - |
Homo sapiens | - |
- |
| microsome | - |
Rattus norvegicus | - |
- |
| microsome | - |
Sus scrofa | - |
- |
| additional information | - |
Homo sapiens | - |
- |
| additional information | - |
Rattus norvegicus | - |
- |
| additional information | - |
Sus scrofa | - |
- |
| nucleus | - |
Rattus norvegicus | 5634 | - |
| nucleus | - |
Sus scrofa | 5634 | - |
Organic Solvent Stability
| Organic Solvent | Comment | Organism |
|---|---|---|
| Acetone | phosphodiesterase I is destroyed during preparation of an acetone powder | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Homo sapiens | - |
| heart | - |
Rattus norvegicus | - |
| intestine | - |
Rattus norvegicus | - |
| intestine | - |
Sus scrofa | - |
| kidney | - |
Homo sapiens | - |
| kidney | - |
Rattus norvegicus | - |
| kidney | - |
Sus scrofa | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Sus scrofa | - |
| liver | human liver and liver neoplasm from human | Homo sapiens | - |
| lung | - |
Rattus norvegicus | - |
| lung | - |
Sus scrofa | - |
| additional information | - |
Homo sapiens | - |
| additional information | - |
Rattus norvegicus | - |
| additional information | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
| additional information | - |
- |
Rattus norvegicus |
| 0.23 | - |
liver microsomes, substrate: p-nitrophenylthymidine 5'-phosphate | Homo sapiens |
| 0.3 | - |
liver microsomes, substrate: p-nitrophenylthymidine 5'-phosphate | Rattus norvegicus |
| 0.47 | - |
kidney microsomes, substrate: p-nitrophenylthymidine 5'-phosphate | Homo sapiens |
| 0.63 | - |
kidney microsomes, substrate: p-nitrophenylthymidine 5'-phosphate | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| p-nitrophenylthymidine 5'-phosphate + H2O | - |
Homo sapiens | 5'-TMP + p-nitrophenol | - |
? | |
| p-nitrophenylthymidine 5'-phosphate + H2O | - |
Rattus norvegicus | 5'-TMP + p-nitrophenol | - |
? | |
| p-nitrophenylthymidine 5'-phosphate + H2O | - |
Sus scrofa | 5'-TMP + p-nitrophenol | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | 9.1 | - |
Homo sapiens |
| 9 | 9.1 | - |
Rattus norvegicus |
| 9 | 9.1 | - |
Sus scrofa |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
