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Literature summary for 3.1.4.1 extracted from
- 5'-Nucleotide phosphodiesterase and alkaline phosphatase in tumor cells: evidence for existence of novel species in the cytosol (1988), Biochim. Biophys. Acta, 966, 99-106.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus |  |
| dithiothreitol | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | - |
Bos taurus | |
| dithiothreitol | - |
Homo sapiens | |
| dithiothreitol | - |
Mus musculus | |
| N-ethylmaleimide | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | |
| N-ethylmaleimide | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus | |
| Zn2+ | - |
Bos taurus | |
| Zn2+ | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | |
| Zn2+ | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus | 5737 | - |
| cytoplasm | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | 5737 | - |
| cytoplasmic membrane | dithiothreitol-sensitive | Mus musculus | - |
- |
| cytoplasmic membrane | dithiothreitol-sensitive | Homo sapiens | - |
- |
| cytoplasmic membrane | dithiothreitol-sensitive | Bos taurus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 67000 | - |
tumor cell line, N-ethylmaleimide-sensitive, gel filtration and SDS-PAGE | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial, liver | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
| fibrosarcoma cell | Meth A tumor | Mus musculus | - |
| FM3A cell | - |
Mus musculus | - |
| HeLa cell | - |
Homo sapiens | - |
| hepatoma cell line | PLC/ PRF/5 human hepatoma | Homo sapiens | - |
| HL-60 cell | - |
Homo sapiens | - |
| intestine | dithiothreitol-sensitive | Bos taurus | - |
| K-562 cell | - |
Homo sapiens | - |
| KB cell | - |
Homo sapiens | - |
| L-1210 cell | - |
Mus musculus | - |
| liver | - |
Homo sapiens | - |
| liver | dithiothreitol-sensitive | Mus musculus | - |
| MH134 cell | - |
Mus musculus | - |
| MM46 cell | - |
Mus musculus | - |
| MOLT-3 cell | - |
Homo sapiens | - |
| myeloma cell line | murine mouse myeloma cell line P3-X63-Ag653 | Mus musculus | - |
| S-180 cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| p-nitrophenylthymidine 5'-phosphate + H2O | - |
Mus musculus | 5'-TMP + p-nitrophenol | - |
? | |
| p-nitrophenylthymidine 5'-phosphate + H2O | - |
Homo sapiens | 5'-TMP + p-nitrophenol | - |
? | |
| p-nitrophenylthymidine 5'-phosphate + H2O | - |
Bos taurus | 5'-TMP + p-nitrophenol | - |
? | |
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