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Literature summary for 3.1.30.1 extracted from
- Active-site characterization of S1 nuclease I (1992), Biochem. J., 285, 489-494.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| amino group modification | at pH 8.0, 65-70% loss of initial activity towards ssDNA, RNA and 3'-AMP after modification of amino groups, lysine residues, with 0.5 mM 2,4,6-trinitrobenzenesulfonic acid | Aspergillus oryzae | |
| citraconylation | reversible block of amino groups, lysine residues, by citraconic anhydride | Aspergillus oryzae | |
| reductive methylation | modification of lysine residues into N,N'-dimethyl lysine | Aspergillus oryzae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | Aspergillus oryzae | - |
5'-phosphomononucleotides + 5'-phosphooligonucleotides | - |
? |  |
| RNA + H2O | Aspergillus oryzae | - |
5'-phosphomononucleotides + 5'-phosphooligonucleotides | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus oryzae | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Aspergillus oryzae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-AMP + H2O | - |
Aspergillus oryzae | adenosine + phosphate | - |
? | |
| DNA + H2O | - |
Aspergillus oryzae | 5'-phosphomononucleotides + 5'-phosphooligonucleotides | - |
? | |
| RNA + H2O | - |
Aspergillus oryzae | 5'-phosphomononucleotides + 5'-phosphooligonucleotides | - |
? | |
| ssDNA + H2O | - |
Aspergillus oryzae | 5'-phosphomononucleotides + 5'-phosphooligonucleotides | - |
? | |
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