Literature summary for 3.1.3.9 extracted from

von Groote-Bidlingmaier, F.; Schmoll, D.; Orth, H.M.; Joost, H.G.; Becker, W.; Barthel, A.
DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression (2003), Biochem. Biophys. Res. Commun., 300, 764-769.

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Cloned(Commentary)

Cloned (Comment)	Organism
the expression of enzyme is transactivated by the transcription factor FKHR, DYRK1 is a specific co activator of FKHR	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-glucose 6-phosphate + H2O	Rattus norvegicus	enzyme is one of the rate-limiting enzymes of hepatic glucogenesis	D-glucose + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glucose 6-phosphate + H2O	-	Rattus norvegicus	D-glucose + phosphate	-	?
D-glucose 6-phosphate + H2O	enzyme is one of the rate-limiting enzymes of hepatic glucogenesis	Rattus norvegicus	D-glucose + phosphate	-	?

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Release 2023.1 (January 2023)