Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.86 extracted from

  • Damen, J.E.; Liu, L.; Rosten, P.; Humphries, R.K.; Jefferson, A.B.; Majerus, P.W.; Krystal, G.
    The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase (1996), Proc. Natl. Acad. Sci. USA, 93, 1689-1693.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.86

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ dependent on Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
145000
-
 gel filtration Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein tyrosine-phosphorylated protein Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
B6SUtA1 cell
-
 Mus musculus
-
bone marrow
-
 Mus musculus
-
lung
-
 Mus musculus
-
skeletal muscle
-
 Mus musculus
-
spleen
-
 Mus musculus
-
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O
-
 Mus musculus 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?
1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Mus musculus 1-phosphatidyl-1D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
SH2-containing inositol phosphatase
-
 Mus musculus
Shc-associated p145 protein
-
 Mus musculus
SHIP
-
 Mus musculus

pI Value

Organism Comment pI Value Maximum pI Value
Mus musculus calculated from amino acid sequence
-
 7.8