Application | Comment | Organism |
---|---|---|
medicine | INPP4A is identified as a novel asthma candidate gene | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | a nonsynonymous single nucleotide polymorphism +110832A/G (Thr/Ala) present within a PEST sequence (peptide sequence rich in proline, glutamic acid, serine and threonine), shows a significant association with atopic asthma. INPP4A alpha3 protein variant from platelets of individuals with AA genotype is found to be more susceptible to degradation, whereas the protein from individuals with GG genotype is less susceptible. Also, the basal levels of INPP4A protein in platelets from individuals with AA genotypes is found to be lower, suggesting poor stability in vivo as well | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q96PE3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
inositol polyphosphate 4 phosphatase A | - |
Homo sapiens |
INPP4A | - |
Homo sapiens |