Literature summary for 3.1.3.53 extracted from

Ryan, T.; Shelton, M.; Lambert, J.P.; Malecova, B.; Boisvenue, S.; Ruel, M.; Figeys, D.; Puri, P.L.; Skerjanc, I.S.
Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway (2013), Circ. Res., 112, 257-266.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	myosin phosphatase subunits protein phosphatase 1beta (PP1beta) and myosin phosphatase targeting subunit (Mypt1) interact with transcription factor Nkx2.5 and inhibit its transcriptional activity	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	myosin phosphatase subunits protein phosphatase 1beta (PP1beta) and myosin phosphatase targeting subunit (Mypt1) interact with transcription factor Nkx2.5 and inhibit its transcriptional activity	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
HEK-293 cell	-	Homo sapiens

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Release 2023.1 (January 2023)