Cloned (Comment) | Organism |
---|---|
various parts of myosin phosphatase targeting subunit GST-fusions expressed in Escherichia coli | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
T696D | part of myosin phosphatase targeting subunit, inhibitory site | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fragment 654-880 of human myosin phosphatase targeting subunit GST-fusion | - |
Sus scrofa | |
fragment 697-880 of human myosin phosphatase targeting subunit GST-fusion | - |
Sus scrofa | |
additional information | phosphorylation of myosin phosphatase targeting subunit on Thr696 and Thr853 (inhibitory sites) results in inhibition | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
GSH affinity chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Sus scrofa | - |
HeLa cell | - |
Homo sapiens | - |
smooth muscle | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[myosin regulatory light chain] phosphate + H2O | from chicken gizzard | Sus scrofa | [myosin regulatory light chain] + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
myosin light chain phosphatase | - |
Homo sapiens |
myosin light chain phosphatase | - |
Sus scrofa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000011 | - |
- |
Sus scrofa | phosphorylated fragment 654-880 of human myosin phosphatase targeting subunit GST-fusion | |
0.00006 | - |
- |
Sus scrofa | phosphorylated fragment 697-880 of human myosin phosphatase targeting subunit GST-fusion | |
0.0014 | - |
- |
Sus scrofa | unphosphorylated fragment 654-880 of human myosin phosphatase targeting subunit GST-fusion | |
0.0061 | - |
- |
Sus scrofa | unphosphorylated fragment 697-880 of human myosin phosphatase targeting subunit GST-fusion |