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Literature summary for 3.1.3.53 extracted from

  • Tomasek, J.J.; Vaughan, M.B.; Kropp, B.P.; Gabbiani, G.; Martin, M.D.; Haaksma, C.J.; Hinz, B.
    Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity (2006), Wound Repair Regen., 14, 313-320.
    View publication on PubMed
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Application

Application Comment Organism
medicine myosin light chain phosphatase pathway is critical in regulating in vivo myofibroblast differentiation during wound healing and fibrocontractive diseases Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
calyculin
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley
-
Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

Source Tissue Comment Organism Textmining
myofibroblast granuloma pouch model of granulation tissue, organ culture Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myosin light-chain phosphate + H2O
-
 Rattus norvegicus myosin light-chain + phosphate
-
 ?
myosin light-chain phosphate + H2O
-
 Rattus norvegicus Sprague-Dawley myosin light-chain + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
MLCP
-
 Rattus norvegicus
[myosin-light-chain] phosphatase
-
 Rattus norvegicus