Application | Comment | Organism |
---|---|---|
additional information | phosphorylation of endogenous inhibitor proteins provides a mechanism for reciprocal coordination of kinase and phosphatase activities | Sus scrofa |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of synthetic segments of MYPT1 (1-19) and (24-41) and MYPT1(1-19) and (24-41) peptides | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CPI-17 | specific inhibitor predominantly expressed in smooth muscles and neurons, phosphorylation of CPI-17 at Thr38 is necessary and sufficient to convert the protein into a potent inhibitor of myosin phosphatase | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aortic smooth muscle | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myosin light-chain phosphate + H2O | muscle | Sus scrofa | myosin light-chain + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | MLCP is a heterotrimer composed of the catalytic subunit belonging to protein phosphatase 1c PPC1, the myosin phosphatase targeting subunit MYPT1, and M21 | Sus scrofa |
Synonyms | Comment | Organism |
---|---|---|
MLCP | - |
Sus scrofa |
myosin light chain phosphatase | - |
Sus scrofa |
myosin phosphatase | - |
Sus scrofa |
MYPT1 | - |
Sus scrofa |