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Literature summary for 3.1.3.53 extracted from

  • Jeon, S.B.; Kim, G.; Kim, J.I.; Seok, Y.M.; Kim, S.H.; Suk, K.; Shin, H.M.; Lee, Y.H.; Kim, I.K.
    Flavone inhibits vascular contraction by decreasing phosphorylation of the myosin phosphatase target subunit (2007), Clin. Exp. Pharmacol. Physiol., 34, 1116-1120.
    View publication on PubMed
Search for more literature for 3.1.3.53

Activating Compound

Activating Compound Comment Organism Structure
U46619 thromboxane A2 analogue at 10-7 mol/L, increases phosphorylation of MYPT1 and regulatory myosin light-chain Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
flavone inhibits U46619-induced regulatory myosin light-chain phosphorylation Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley
-
Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

Source Tissue Comment Organism Textmining
aortic smooth muscle thorax Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myosin light-chain phosphate + H2O
-
 Rattus norvegicus myosin light-chain + phosphate
-
 ?
myosin light-chain phosphate + H2O
-
 Rattus norvegicus Sprague-Dawley myosin light-chain + phosphate
-
 ?
regulatory myosin light-chain phosphate + H2O
-
 Rattus norvegicus regulatory myosin light-chain + phosphate
-
 ?
regulatory myosin light-chain phosphate + H2O
-
 Rattus norvegicus Sprague-Dawley regulatory myosin light-chain + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
MLCP
-
 Rattus norvegicus
myosin light chain phosphatase
-
 Rattus norvegicus
myosin phosphatase
-
 Rattus norvegicus
MYPT1
-
 Rattus norvegicus