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Literature summary for 3.1.3.5 extracted from

  • Spychala, J.; Madrid-Marina, V.; Fox, I.H.
    High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP (1988), J. Biol. Chem., 263, 18759-18765.
    View publication on PubMed
Search for more literature for 3.1.3.5

Activating Compound

Activating Compound Comment Organism Structure
2,3-diphosphoglycerate activation Homo sapiens
ATP activation Homo sapiens
dATP activation Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.09
-
 5'-IMP presence of 3 mM ATP Homo sapiens
0.13
-
 5'-IMP presence of 3 mM ATP plus 4 mM phosphate Homo sapiens
0.33
-
 5'-IMP
-
 Homo sapiens
0.54
-
 5'-IMP presence of 4 mM phosphate Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-dIMP + H2O i.e. 2'-deoxyinosine 5'-phosphate Homo sapiens deoxyinosine + phosphate
-
 ?
5'-dIMP + H2O 23% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens deoxyinosine + phosphate
-
 ?
5'-GMP + H2O 85% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens guanosine + phosphate
-
 ?
5'-IMP + H2O preferred substrate Homo sapiens inosine + phosphate
-
 ?
5'-UMP + H2O 14% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens uridine + phosphate
-
 ?
5'-XMP + H2O 23% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens xanthosine + phosphate
-
 ?