Activating Compound | Comment | Organism | Structure |
---|---|---|---|
CCl4 | livers from wild type mice treated with CCl4 (1.25 ml/kg) release 2-3fold higher levels of adenosine than livers from comparably treated CD73KO mice | Mus musculus | |
ethanol | livers from wild type mice treated with ethanol (2 g/kg of 20% ethanol) release 2-3fold higher levels of adenosine than livers from comparably treated CD73KO mice | Mus musculus | |
Thioacetamide | livers from wild type mice treated with thioacetamide (100 mg/kg) release 2-3fold higher levels of adenosine than livers from comparably treated CD73KO mice | Mus musculus |
Application | Comment | Organism |
---|---|---|
medicine | CD73 plays an important role in adenosine generation in the liver, the extracellular adenosine generated by CD73 is a critical mediator of hepatic fibrosis | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | - |
Mus musculus | adenosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CD73 | - |
Mus musculus |
ecto-5'-nucleotidase | - |
Mus musculus |