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Literature summary for 3.1.3.48 extracted from

  • Pot, D.A.; Woodford, T.A.; Remboutsika, E.; Haun, R.S.; Dixon, J.E.
    Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase (1991), J. Biol. Chem., 266, 19688-19696.
    View publication on PubMed
Search for more literature for 3.1.3.48

Cloned(Commentary)

Cloned (Comment) Organism
catalytic domain of receptor-like protein tyrosine phosphatase Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
iodoacetic acid
-
 Rattus norvegicus
molybdate
-
 Rattus norvegicus
N-ethylmaleimide
-
 Rattus norvegicus
p-hydroxymercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.118
-
 DRVpYIHPFHL
-
 Rattus norvegicus
0.42
-
 4-nitrophenyl phosphate
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q64604
-
-

Purification (Commentary)

Purification (Comment) Organism
catalytic domain Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
16.2
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl phosphate + H2O
-
 Rattus norvegicus 4-nitrophenol + phosphate
-
 ?
DRVpYIHPFHL + H2O
-
 Rattus norvegicus DRVYIHPFHL + phosphate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.1
-
 DRVpYIHPFHL
-
 Rattus norvegicus
6.1
-
 4-nitrophenyl phosphate
-
 Rattus norvegicus