Cloned (Comment) | Organism |
---|---|
expression of truncated forms encoding the catalytic domain which is independent of the regulatory influence of the C-terminus | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
phosphotyrosine phosphatase 1B | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | truncated enzyme forms with reduced Km for 4-nitrophenyl phosphate | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H3VO4 | - |
Homo sapiens | |
heparin | - |
Homo sapiens | |
molybdate | - |
Homo sapiens | |
poly(Glu-Tyr) | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.08 | - |
4-nitrophenyl phosphate | truncated enzyme b-PTP1B(DELTA321) | Homo sapiens | |
0.1 | - |
4-nitrophenyl phosphate | truncated enzyme PTP1B(DELTA321) | Homo sapiens | |
0.11 | - |
4-nitrophenyl phosphate | truncated enzyme b-PTP1B(DELTA299) | Homo sapiens | |
0.38 | - |
4-nitrophenyl phosphate | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C, 50 mM Hepes, pH 7.2, 0.1% 2-mercaptoethanol, 50% glycerol | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl phosphate + H2O | - |
Homo sapiens | 4-nitrophenol + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphotyrosine phosphatase 1B | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
substrate 4-nitrophenyl phosphate | Homo sapiens |