Cloned (Comment) | Organism |
---|---|
full length form and a truncated form lacking the SH-domains and exhibiting a higher catalytic activity, GenBank, EMBL Data Bank L07527 | Homo sapiens |
General Stability | Organism |
---|---|
sensitive to freezing and thawing | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H3VO4 | - |
Homo sapiens | |
heparin | - |
Homo sapiens | |
molybdate | - |
Homo sapiens | |
NaF | slight inhibition | Homo sapiens | |
Phenylarsine oxide | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.059 | 0.789 | platelet-derived growth factor receptor | value varies with the point of tyrosine phosphorylation, values for truncated enzyme reduced relative to wild-type form | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q06124 | GenBank, EMBL Data Bank L07527 | - |
Storage Stability | Organism |
---|---|
-70°C, 20% glycerol, no loss of activity | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl phosphate + H2O | - |
Homo sapiens | 4-nitrophenol + phosphate | - |
? | |
platelet-derived growth factor receptor + H2O | - |
Homo sapiens | ? + phosphate | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.66 | 7.2 | platelet-derived growth factor receptor | value varies with the point ot tyrosine phosphorylation, values for truncated enzyme increased relative to wild-type form | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.3 | - |
- |
Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
unstable in imidazole buffers | Homo sapiens |