Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.48 extracted from

  • Modesti, A.; Marzocchini, R.; Raugei, G.; Chiti, F.; Sereni, A.; Magherini, F.; Ramponi, G.
    Cloning, expression and characterization of new human low Mr phosphotyrosine protein phosphatase originating by alternative splicing (1998), FEBS Lett., 431, 111-115.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of splicing variant SV3 of LMW-PTP in Escherichia coli Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
76770
-
splicing variant SV3 of LMW-PTP, calculation from nucleotide sequence Homo sapiens
77000
-
x * 77000, splicing variant SV3 of LMW-PTP, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens LMW-PTP is involved in the negative regulation of the mitogenic stimulus starting from the activated PDGF receptor. The interaction between LMW-PTP results in the dephosphorylation of the PDGF-R phosphortyrosine and a negative regulation of the mitogenic signal ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information LMW-PTP is involved in the negative regulation of the mitogenic stimulus starting from the activated PDGF receptor. The interaction between LMW-PTP results in the dephosphorylation of the PDGF-R phosphortyrosine and a negative regulation of the mitogenic signal Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
? x * 77000, splicing variant SV3 of LMW-PTP, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
LMW-PTP
-
Homo sapiens