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Literature summary for 3.1.3.48 extracted from

  • Tonks, N.K.; Diltz, C.D.; Fischer, E.H.
    Purification of the major protein-tyrosine-phosphatases of human placenta (1988), J. Biol. Chem., 263, 6722-6730.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-
plasma membrane
-
Homo sapiens 5886
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
19.7
-
cytoplasmic enzyme Homo sapiens
42.7
-
membrane-bound enzyme Homo sapiens

Storage Stability

Storage Stability Organism
-70°C, 50 mM imidazole-HCl, pH 7.2, 2 mM EDTA, 0.1% v/v 2-mercaptoethanol, 1 mM benzamidine, 0.002% w/v PMSF, 50% v/v glycerol, half-life: 3 months Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lysozyme + H2O reduced, carboxymethylated and maleylated Homo sapiens ? + phosphate
-
?

Subunits

Subunits Comment Organism
? 35000-40000, catalytic subunit, SDS-PAGE Homo sapiens