Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | Mus musculus | - |
[a protein]-tyrosine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
glutathione-Sepharose or Talon metal affinity resin bead chromatography | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
striatum | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphorylated proline-rich tyrosine kinase 2 + H2O | the enzyme directly binds to and dephosphorylates proline-rich tyrosine kinase 2 at Tyr402 | Mus musculus | proline-rich tyrosine kinase 2 + phosphate | - |
? | |
[a protein]-tyrosine phosphate + H2O | - |
Mus musculus | [a protein]-tyrosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
STEP | - |
Mus musculus |
striatal-enriched protein-tyrosine phosphatase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | striatal-enriched protein-tyrosine phosphatase regulates proline-rich tyrosine kinase 2 activity | Mus musculus |