Protein Variants | Comment | Organism |
---|---|---|
C11A | inactive | Mycobacterium tuberculosis |
C16A | the mutant retains the activity similar to the wild type enzyme | Mycobacterium tuberculosis |
C53A | the mutant is insensitive to S-nitrosoglutathione treatment | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-nitrosoglutathione | S-nitrosoglutathione treatment decreases the catalytic activity parameters of PtpA by half | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | Mycobacterium tuberculosis | - |
[a protein]-tyrosine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
S-nitrosylation | - |
Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | - |
Mycobacterium tuberculosis | [a protein]-tyrosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LMW-PTP | - |
Mycobacterium tuberculosis |
protein tyrosine phosphatase | - |
Mycobacterium tuberculosis |
PtpA | - |
Mycobacterium tuberculosis |