Inhibitors | Comment | Organism | Structure |
---|---|---|---|
potassium bisperoxo(1,10-phenanthroline)oxovanadate(V) | i.e. [bpV(phen)], the peroxovanadium compound is a stable, potent and selective protein tyrosine phosphatase inhibitor. It protects dorsal column sensory axons and white matter and rescues sensory-evoked potentials in vivo after treatement with PTP or spinal cord injury, overview | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
adult female Sprague Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | - |
Rattus norvegicus | - |
spinal cord | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
protein tyrosine phosphatase | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
malfunction | protein tyrosine phosphatases inactivate neurotrophic factor receptors and downstream intracellular signaling molecules causing neurodegeneration and loss of sensoric functions, overview | Rattus norvegicus |
additional information | small-molecule protein tyrosine phosphatase inhibition is a neuroprotective treatment after spinal cord injury in adult rats | Rattus norvegicus |