Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,4-dihydroxy-6-methylbenzoic acid | 45% inhibition of PTPB1 at 0.178 mM | Homo sapiens | |
3-hydroxy-4-(methoxycarbonyl)-5-methylphenyl 4-(beta-D-galactopyranosyloxy)-2-hydroxy-6-pentadecylbenzoate | - |
Homo sapiens | |
4-(beta-D-galactopyranosyloxy)-2-hydroxy-6-pentadecylbenzoic acid | - |
Homo sapiens | |
4-[(2,4-dihydroxy-6-pentadecylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid | - |
Homo sapiens | |
aquastatin A | derived from marine fungus Cosmospora sp. SF-5060, competitive inhibition | Homo sapiens | |
ursolic acid | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | protein tyrosine phosphatase 1B, PTP1B, is an intracellular non-receptor type PTP | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl phosphate + H2O | - |
Homo sapiens | 4-nitrophenol + phosphate | - |
? | |
additional information | protein tyrosine phosphatase 1B, PTP1B, is an intracellular non-receptor type PTP | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
protein tyrosine phosphatase 1B | - |
Homo sapiens |
PTP1B | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00001 | - |
aquastatin A | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00019 | - |
- |
Homo sapiens | aquastatin A | |
0.00022 | - |
- |
Homo sapiens | 4-[(2,4-dihydroxy-6-pentadecylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid | |
0.00059 | - |
- |
Homo sapiens | 4-(beta-D-galactopyranosyloxy)-2-hydroxy-6-pentadecylbenzoic acid | |
0.0025 | - |
- |
Homo sapiens | ursolic acid | |
0.017 | - |
- |
Homo sapiens | 3-hydroxy-4-(methoxycarbonyl)-5-methylphenyl 4-(beta-D-galactopyranosyloxy)-2-hydroxy-6-pentadecylbenzoate |