Inhibitors | Comment | Organism | Structure |
---|---|---|---|
betulinic acid | 95.1% PTP1B inhibitory activity with 0.0007 mg/ml | Homo sapiens | |
betulinic acid methyl ester | 89.4% PTP1B inhibitory activity with 0.00093 mg/ml | Homo sapiens | |
dehydrocostuslactone | 86.2% PTP1B inhibitory activity with 0.00651 mg/ml | Homo sapiens | |
mokko lactone | 93.1% PTP1B inhibitory activity with 0.00141 mg/ml | Homo sapiens | |
additional information | not inhibited by costunolide, 11beta,13-dihydrocostunolide, reynosin, 1beta-hydroxy arbusculin A, santamarine, alpha-costol, beta-sitosterol, aplotaxene, and alpha-amyrin stearate | Homo sapiens | |
RK-682 | 98.5% PTP1B inhibitory activity with 0.0012 mg/ml | Homo sapiens | |
ursolic acid | 99% PTP1B inhibitory activity with 0.0007 mg/ml | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl phosphate + H2O | - |
Homo sapiens | 4-nitrophenol + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
protein tyrosine phosphatase 1B | - |
Homo sapiens |
PTP1B | - |
Homo sapiens |
PTPase | - |
Homo sapiens |