Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 DE3 cells | Drosophila melanogaster |
Protein Variants | Comment | Organism |
---|---|---|
C237S | catalytically dead mutant | Drosophila melanogaster |
D203A | substrate-trapping mutant | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Drosophila melanogaster | 16020 | - |
nucleus | - |
Drosophila melanogaster | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
61000 | - |
nucleus-localized enzyme form, calculated from amino acid sequence | Drosophila melanogaster |
62100 | - |
membrane-localized enzyme form, calculated from amino acid sequence | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA Sepharose column chromatography | Drosophila melanogaster |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
S2 cell | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphorylated Abelson interacting protein + H2O | - |
Drosophila melanogaster | Abelson interacting protein + phosphate | - |
? | |
phosphorylated Abl tyrosine kinase + H2O | - |
Drosophila melanogaster | Abl tyrosine kinase + phosphate | - |
? | |
phosphorylated Ack protein + H2O | - |
Drosophila melanogaster | Ack protein + phosphate | - |
? | |
phosphorylated Down syndrome cell adhesion molecule + H2O | - |
Drosophila melanogaster | Down syndrome cell adhesion molecule + phosphate | - |
? | |
phosphorylated eukaryotic-initiation-factor-4G + H2O | - |
Drosophila melanogaster | eukaryotic-initiation-factor-4G + phosphate | - |
? | |
phosphorylated fragile X related + H2O | - |
Drosophila melanogaster | fragile X related + phosphate | - |
? | |
phosphorylated HEM protein + H2O | - |
Drosophila melanogaster | HEM protein + phosphate | - |
? | |
phosphorylated hepatocyte growth factor regulated tyrosine kinase substrate + H2O | - |
Drosophila melanogaster | hepatocyte growth factor regulated tyrosine kinase substrate + phosphate | - |
? | |
phosphorylated Hsc-70-4 + H2O | - |
Drosophila melanogaster | Hsc-70-4 + phosphate | - |
? | |
phosphorylated IGF-II mRNA-binding protein + H2O | - |
Drosophila melanogaster | IGF-II mRNA-binding protein + phosphate | - |
? | |
phosphorylated Lasp protein + H2O | - |
Drosophila melanogaster | Lasp protein + phosphate | - |
? | |
phosphorylated PDGF- and VEGF-receptor related + H2O | - |
Drosophila melanogaster | PDGF- and VEGF-receptor related + phosphate | - |
? | |
phosphorylated poly(A)-binding protein + H2O | - |
Drosophila melanogaster | poly(A)-binding protein + phosphate | - |
? | |
phosphorylated polychaetoid + H2O | - |
Drosophila melanogaster | polychaetoid + phosphate | - |
? | |
phosphorylated rasputin + H2O | - |
Drosophila melanogaster | rasputin + phosphate | - |
? | |
phosphorylated RhoGAP15B + H2O | - |
Drosophila melanogaster | RhoGAP15B + phosphate | - |
? | |
phosphorylated SCAR + H2O | - |
Drosophila melanogaster | SCAR + phosphate | - |
? | |
phosphorylated SH3PX1 + H2O | - |
Drosophila melanogaster | SH3PX1 + phosphate | - |
? | |
phosphorylated specifically Rac1-associated protein 1 + H2O | - |
Drosophila melanogaster | specifically Rac1-associated protein 1 + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dPTP61F | dPTP61F plays a central role in counteracting PTK-mediated signaling pathways as well as in regulating actin reorganization and remodeling through tyrosine dephosphorylation of critical substrates in Drosophila | Drosophila melanogaster |
protein tyrosine phosphatase | - |
Drosophila melanogaster |
PTK | - |
Drosophila melanogaster |
PTP | - |
Drosophila melanogaster |