Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | activation of SPH-1 and SPH-2 is accompanied by reduced responsiveness to aggregating agents, phosphorylation of SPH-1 and SPH-2 introduces docking sites for adaptor molecules like growth factor receptor-bound protein 2 regulating further signaling to integrin alphaIIbbeta3 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
hematopoietic cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | activation of SPH-1 and SPH-2 is accompanied by reduced responsiveness to aggregating agents, phosphorylation of SPH-1 and SPH-2 introduces docking sites for adaptor molecules like growth factor receptor-bound protein 2 regulating further signaling to integrin alphaIIbbeta3 | Homo sapiens | ? | - |
? | |
phosphorylated p38 mitogen-activated protein kinase + H2O | - |
Homo sapiens | p38 mitogen-activated protein kinase + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SH2 domain-containing tyrosine phosphatase-1 | - |
Homo sapiens |
SH2 domain-containing tyrosine phosphatase-2 | - |
Homo sapiens |
SHP-1 | - |
Homo sapiens |
SHP-2 | - |
Homo sapiens |