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Literature summary for 3.1.3.48 extracted from

  • Tiran, Z.; Peretz, A.; Sines, T.; Shinder, V.; Sap, J.; Attali, B.; Elson, A.
    Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells (2006), Mol. Biol. Cell, 17, 4330-4342.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK293 cells Mus musculus

Protein Variants

Protein Variants Comment Organism
D245A catalytically inactive Mus musculus
D437A catalytically inactive Mus musculus
R283M catalytically inactive Mus musculus
R340M catalytically inactive Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Schwann cell
-
Mus musculus
-
sciatic nerve
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphorylated voltage-gated potassium channel subunit Kv2.1 + H2O
-
Mus musculus voltage-gated potassium channel subunit Kv2.1 + phosphate
-
?

Synonyms

Synonyms Comment Organism
PTPalpha
-
Mus musculus
PTPepsilon
-
Mus musculus
tyrosine phosphatase alpha
-
Mus musculus
tyrosine phosphatase epsilon
-
Mus musculus