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Literature summary for 3.1.3.48 extracted from

  • Iervolino, A.; Iuliano, R.; Trapasso, F.; Viglietto, G.; Melillo, R.M.; Carlomagno, F.; Santoro, M.; Fusco, A.
    The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins (2006), Cancer Res., 66, 6280-6287.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 DE3 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
C1239S catalytically inactive Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
Homo sapiens
-
thyroid cancer cell line
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphorylated RET(C634R) oncoprotein + H2O dephosphorylation at Tyr905 and Tyr1062 Homo sapiens RET(C634R) oncoprotein + phosphate
-
?
phosphorylated RET-MEN2A oncoprotein + H2O dephosphorylation at Tyr905 and Tyr1062 Homo sapiens RET-MEN2A oncoprotein + phosphate
-
?
phosphorylated RET/PTC1 oncoprotein + H2O dephosphorylation at Tyr905 and Tyr1062 Homo sapiens RET/PTC1 oncoprotein + phosphate
-
?

Synonyms

Synonyms Comment Organism
PTPRJ
-
Homo sapiens
receptor-type protein tyrosine phosphatase J
-
Homo sapiens