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Literature summary for 3.1.3.48 extracted from

  • Aguirre-Garcia, M.M.; Escalona-Montano, A.R.; Bakalara, N.; Perez-Torres, A.; Gutierrez-Kobeh, L.; Becker, I.
    Leishmania major: detection of membrane-bound protein tyrosine phosphatase (2006), Parasitology, 132, 641-649.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Ammonium molybdate complete inhibition of enzyme isolated from metacyclic stage, 75% inhibition of enzyme from procyclic stage Leishmania major
dephostatin complete inhibition of enzyme isolated from metacyclic stage, 28% inhibition of enzyme from procyclic stage Leishmania major
okadaic acid complete inhibition of enzyme isolated from metacyclic stage, 35% inhibition of enzyme from procyclic stage Leishmania major
sodium orthovanadate complete inhibition of enzyme isolated from metacyclic stage, 30% inhibition of enzyme from procyclic stage Leishmania major
sodium tungstate complete inhibition of enzyme isolated from metacyclic stage, 50% inhibition of enzyme from procyclic stage Leishmania major
Trifluoperazine complete inhibition of enzyme isolated from metacyclic stage, 18% inhibition of enzyme from procyclic stage Leishmania major

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm in procyclic stage, scattered throughout the cytoplasm Leishmania major 5737
-
membrane in metacyclic stage, membrane-associated Leishmania major 16020
-

Organism

Organism UniProt Comment Textmining
Leishmania major
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
promastigote
-
Leishmania major
-

Subunits

Subunits Comment Organism
? x * 55000-60000, SDS-PAGE Leishmania major