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Literature summary for 3.1.3.48 extracted from

  • Rouleau, C.; Roy, A.; St Martin, T.; Dufault, M.R.; Boutin, P.; Liu, D.; Zhang, M.; Puorro-Radzwill, K.; Rulli, L.; Reczek, D.; Bagley, R.; Byrne, A.; Weber, W.; Roberts, B.; Klinger, K.; Brondyk, W.; Nacht, M.; Madden, S.; Burrier, R.; Shankara, S.; Teicher, B.A.
    Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function (2006), Mol. Cancer Ther., 5, 219-229.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
phorbol 12-myristate 13-acetate enzyme gene is among the 10 genes with the largest increased in expression upon phorbol 12-myristate 13-acetate stimulation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BT-474 cell breast carcinoma, high expression Homo sapiens
-
carcinoma cell enzyme mRNA levels vary markedly in different tumor cell types, positive correlation between enzyme mRNA and protein level Homo sapiens
-
endothelium increased expression in umbilical vascular endothelial cells and microvascular endothelial cells upon exposure to phorbol 12-myristate 13-acetate Homo sapiens
-
HCT-116 cell colon carcinaoma cell, high expression Homo sapiens
-
MCF-7 cell breast carcinoma, high expression Homo sapiens
-
SK-N-AS cell neuroblastoma cell, high expression of enzyme Homo sapiens
-

Synonyms

Synonyms Comment Organism
PRL-3
-
Homo sapiens