Application | Comment | Organism |
---|---|---|
medicine | transgenic mice overexpressing enzyme in muscle at levels similar to those observed in insulin-resistant humans. Insulin-stimulated insulin receptor tyrosyl phosphorylation and phosphatidylinositol 3'-kinase activity are impaired by 35% and 40-60% resp. Whole body glucose disposal and muscle glucose uptake are decreased by 40-50% | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
transgenic expression in mice muscle | - |
Synonyms | Comment | Organism |
---|---|---|
PTP1B | - |
Homo sapiens |