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Literature summary for 3.1.3.48 extracted from

  • Na, M.; Oh, W.K.; Kim, Y.H.; Cai, X.F.; Kim, S.; Kim, B.Y.; Ahn, J.S.
    Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum (2006), Bioorg. Med. Chem. Lett., 16, 3061-3064.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
16alphaH,17-isovaleryloxy-ent-kauran-19-oic acid diterpenoid isolated from Acanthopanax koreanum, 50% inhibition at 0.007 mM, noncompetitive Homo sapiens
acanthoic acid diterpenoid isolated from Acanthopanax koreanum, 50% inhibition at 0.024 mM Homo sapiens
ent-kaur-16-en-19-oic acid diterpenoid isolated from Acanthopanax koreanum, 50% inhibition at 0.020 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
comercial preparation
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.01
-
16alphaH,17-isovaleryloxy-ent-kauran-19-oic acid pH 6.0, 30°C Homo sapiens