Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Cyclic AMP dependent protein kinase | - |
Rattus norvegicus | |
Cyclic AMP dependent protein kinase | - |
Pelophylax lessonae | |
glycerol 1-phosphate | - |
Rattus norvegicus | |
glycerol 1-phosphate | counteracts fructose 6-phosphate inhibition | Pelophylax lessonae | |
MgGTP2- | - |
Pelophylax lessonae | |
phosphate | - |
Rattus norvegicus | |
phosphate | counteracts inhibition by fructose-6-phosphate | Pelophylax lessonae |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fructose 6-phosphate | - |
Pelophylax lessonae | |
fructose 6-phosphate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0004 | - |
fructose 2,6-bisphosphate | - |
Pelophylax lessonae | |
0.0006 | - |
fructose 2,6-bisphosphate | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
53300 | - |
53300, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
fructose 2,6-bisphosphate + H2O | Rattus norvegicus | - |
? | - |
? | |
fructose 2,6-bisphosphate + H2O | Pelophylax lessonae | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pelophylax lessonae | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
5600fold | Pelophylax lessonae |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate | bifunctional enzyme: 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase | Rattus norvegicus | |
beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate | bifunctional enzyme: 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase | Pelophylax lessonae |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | skeletal | Rattus norvegicus | - |
muscle | skeletal | Pelophylax lessonae | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fructose 2,6-bisphosphate + H2O | - |
Rattus norvegicus | fructose 6-phosphate + phosphate | - |
? | |
fructose 2,6-bisphosphate + H2O | - |
Pelophylax lessonae | fructose 6-phosphate + phosphate | - |
? | |
fructose 2,6-bisphosphate + H2O | - |
Rattus norvegicus | ? | - |
? | |
fructose 2,6-bisphosphate + H2O | - |
Pelophylax lessonae | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 53300, SDS-PAGE | Rattus norvegicus |
dimer | 53900-55800, SDS-PAGE | Pelophylax lessonae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
- |
Rattus norvegicus |
5.5 | - |
- |
Pelophylax lessonae |