Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | astrocytoma cell, glioblastoma cell and non neoplastic brain tissue | Homo sapiens | - |
additional information | PFKFB3 protein level but not mRNA expression is up-regulated in high-grade astrocytomas | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-D-fructose 2,6-bisphosphate + H2O | - |
Homo sapiens | D-fructose 6-phosphate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
6-phosphofructo-2-kinase/fructose-2 6-biphosphatase | - |
Homo sapiens |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (gene PFKFB3) | bifunctional enzyme | Homo sapiens |
PFK-2/FBPase-2 | - |
Homo sapiens |
PFKFB3 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the protein levels are markedly elevated in high-grade astrocytomas relative to low-grade astrocytomas and corresponding non-neoplastic brain tissue, whereas no significant increase of PFKFB3 mRNA is observed in high-grade astrocytomas | additional information |