Activating Compound | Comment | Organism | Structure |
---|---|---|---|
(1S)-1,5-anhydro-1-{[(1R,2R,3R,4S,5S,6S)-2,3,4,5-tetrahydroxy-6-methoxycyclohexyl]methyl}-D-galactitol | i.e. C-INS-2-OH the deaminated analogue of C-INS-2 | Rattus norvegicus | |
(1S)-2-amino-1,5-anhydro-2-deoxy-1-{[(1R,2R,3R,4S,5S,6S)-2,3,4,5-tetrahydroxy-6-methoxycyclohexyl]methyl}-D-galactitol | i.e. C-INS-2, the C-glycoside of INS-2 | Rattus norvegicus | |
4-O-beta-D-galactosaminyl-3-O-methyl-D-chiro-inositol | i.e. INS-2, allosteric activation, docking study using crystal structure of the enzyme PDHP1, PDB ID 2PNQ, and mechanism, overview | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
PDHP | - |
Rattus norvegicus |
pyruvate dehydrogenase phosphatase | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | allosteric activation of pyruvate dehydrogenase phosphatase and protein phosphatase 2Calpha leads to insulin-mimetic and insulin-sensitizing effects | Rattus norvegicus |