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Literature summary for 3.1.3.43 extracted from
- Differential effects of two mutations at arginine-234 in the alpha subunit of human pyruvate dehydrogenase (2001), Arch. Biochem. Biophys., 395, 121-128.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | dephosphorylation of substrate and substrate mutants R234Q, R234G occurs at similar rates at phosphorylation sites 1 and 2, the rate of dephosphorylation of site 3 is about 50% of wild type in substrate mutant R234Q | Homo sapiens | ? | - |
? |  |
| [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | - |
Homo sapiens | [pyruvate dehydrogenase (lipoamide)] + phosphate | - |
? | |
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Release 2023.1 (January 2023)
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