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Literature summary for 3.1.3.4 extracted from
- Involvement of lysophosphatidic acid, sphingosine 1-phosphate and ceramide 1-phosphate in the metabolization of phosphatidic acid by lipid phosphate phosphatases in bovine rod outer segments (2008), Neurochem. Res., 33, 1205-1215.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | light regulation of the lipid phosphate phosphatases, overview | Bos taurus | |
| sphingosine 1-phosphate | activates overall cell lipid phosphate phosphatase activities by about 13% | Bos taurus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | light regulation of the lipid phosphate phosphatases, overview | Bos taurus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Bos taurus | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| a 3-sn-phosphatidate + H2O | Bos taurus | dephosphorylation of these lipids terminates their signaling actions and generates products with additional biological activities or metabolic fates, overview | a 1,2-diacyl-sn-glycerol + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | - |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| retina | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2-diacyl-sn-glycerol 3-phosphate + H2O | - |
Bos taurus | 1,2-diacyl-sn-glycerol + phosphate | - |
? | |
| a 3-sn-phosphatidate + H2O | dephosphorylation of these lipids terminates their signaling actions and generates products with additional biological activities or metabolic fates, overview | Bos taurus | a 1,2-diacyl-sn-glycerol + phosphate | - |
? | |
| lysophosphatidic acid + H2O | - |
Bos taurus | ? + phosphate | - |
? | |
| additional information | competition between phosphatidic acid, lysophosphatidic acid by the active site of LPPs is modulated by rod outer segment illumination state and by rod outer segment protein association/dissociation, overview | Bos taurus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| More | the enzyme belongs to the group of lipid phosphate phosphatases | Bos taurus |
| PAP2 | - |
Bos taurus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
assay at | Bos taurus |
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Release 2023.1 (January 2023)
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