Any feedback?
Literature summary for 3.1.3.4 extracted from
- Enzymatic analysis of lipid phosphate phosphatases (2006), Methods, 39, 169-179.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | radiolabeled and fluorescent lipid substrates for the detection, quantitation and analysis of the enzymatic activities of the LPPs measured using intact or broken cell preparations as the source of enzyme | Mus musculus |
| analysis | radiolabeled and fluorescent lipid substrates for the detection, quantitation and analysis of the enzymatic activities of the LPPs measured using intact or broken cell preparations as the source of enzyme | Homo sapiens |
| analysis | radiolabeled and fluorescent lipid substrates for the detection, quantitation and analysis of the enzymatic activities of the LPPs measured using intact or broken cell preparations as the source of enzyme | Rattus norvegicus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| transient and stable overexpression in HEK-293 cells, baculovirus vectors for recombinant expression of LPPs in cultured Sf9 cells | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | insensitive to inhibition by the alkylating agent N-ethyl maleimide | Homo sapiens | |
| additional information | insensitive to inhibition by the alkylating agent N-ethyl maleimide | Rattus norvegicus | |
| propranolol | moderately effective inhibitor of LPP activity | Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Mus musculus | 16020 | - |
| membrane | - |
Homo sapiens | 16020 | - |
| membrane | - |
Rattus norvegicus | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | independent of divalent metal ions | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
| additional information | Swiss 3T3 cell | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ceramide 1-phosphate + H2O | - |
Homo sapiens | ceramide + phosphate | - |
? | |
| ceramide 1-phosphate + H2O | - |
Rattus norvegicus | ceramide + phosphate | - |
? | |
| lyso-phosphatidic acid + H2O | - |
Homo sapiens | monoacylglycerol + phosphate | - |
? | |
| lyso-phosphatidic acid + H2O | - |
Rattus norvegicus | monoacylglycerol + phosphate | - |
? | |
| phosphatidic acid + H2O | - |
Homo sapiens | diacylglycerol + phosphate | - |
? | |
| phosphatidic acid + H2O | - |
Rattus norvegicus | diacylglycerol + phosphate | - |
? | |
| sphingosine 1-phosphate + H2O | - |
Homo sapiens | sphingosine + phosphate | - |
? | |
| sphingosine 1-phosphate + H2O | - |
Rattus norvegicus | sphingosine + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LPP1 | - |
Homo sapiens |
| LPP2 | - |
Homo sapiens |
| LPP3 | - |
Mus musculus |
| LPP3 | - |
Homo sapiens |
| LPP3 | - |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
