Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dihydrosphingosine | - |
Homo sapiens | |
dimethylsphingosine | - |
Homo sapiens | |
F- | NaF | Homo sapiens | |
Mg2+ | MgCl2 | Homo sapiens | |
NEM | no inhibition | Homo sapiens | |
phosphatidic acid | competitive inhibition | Homo sapiens | |
propanolol | - |
Homo sapiens | |
sphingosine | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.4 | - |
dioctanoyl phosphatidic acid | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Homo sapiens | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme may play an important role in regulating inflammatory cell responses to extracellular phosphatidic acid in biological system | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.1175 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
didecanoyl phosphatidic acid + H2O | - |
Homo sapiens | 1,2-didecanoyl-sn-glycerol + phosphate | - |
? | |
dihexanoyl phosphatidic acid + H2O | - |
Homo sapiens | 1,2-dihexanoyl-sn-glycerol + phosphate | - |
? | |
dimyristoyl phosphatidic acid + H2O | - |
Homo sapiens | 1,2-dimyristoyl-sn-glycerol + phosphate | - |
? | |
dioctanoyl phosphatidic acid + H2O | - |
Homo sapiens | 1,2-dioctanoyl-sn-glycerol + phosphate | - |
? | |
dioleoyl phosphatidic acid + H2O | - |
Homo sapiens | 1,2-dioleoyl-sn-glycerol + phosphate | - |
? | |
dipalmitoyl phosphatidic acid + H2O | - |
Homo sapiens | ? | - |
? | |
lysophosphatidate + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | both long and short chain lysophosphatidic acids are hydrolyzed at rates comparable with that observed for short chain phosphatidic acids | Homo sapiens | ? | - |
? | |
additional information | the enzyme may play an important role in regulating inflammatory cell responses to extracellular phosphatidic acid in biological system | Homo sapiens | ? | - |
? | |
octanoyl lysophosphatidic acid + H2O | - |
Homo sapiens | ? | - |
? | |
oleoyl phosphatidic acid + H2O | - |
Homo sapiens | ? | - |
? | |
phosphatidic acid + H2O | - |
Homo sapiens | 1,2-diacyl-sn-glycerol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 45000-52000, SDS-PAGE | Homo sapiens |