Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | cytoplasmic protein in keratinocytes that primarily localizes to endosomes | Homo sapiens | 5737 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
keratinocyte | - |
Homo sapiens | - |
skin | - |
Homo sapiens | - |
squamous cell carcinoma cell | highly induced in squamous cell carcinoma | Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
homodimer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PSPH | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | highly induced in squamous cell carcinoma | up |
General Information | Comment | Organism |
---|---|---|
malfunction | knock down of PSPH dramatically diminishes squamous cell carcinoma cell proliferation and cyclin D1 levels in the presence of exogenous of L-serine production suggesting a non-canonical role for PSPH in epithelial carcinogenesis | Homo sapiens |